Are You at Risk for Lung Cancer?

Medically Reviewed by Prince Ntiamoah, MD
Written by J. GuanFeb 1, 20247 min read
Man Holding Chest

Source: Shutterstock

Ever wondered if you are at risk for lung cancer? Let us talk about risk factors – things that can increase your chances of developing a disease like cancer. It's important to know that having one or more risk factors does not mean you willl definitely get cancer. Sometimes, people who develop lung cancer have few or no identifiable risk factors.

Here is the scoop: some risk factors, such as smoking, can be avoided. Others, like age and family history, are beyond our control. And here is an interesting twist – certain risk factors may have a stronger link to specific types of lung cancer. It is like pieces of a puzzle coming together.

What is fascinating is how combined risk factors can add up, potentially increasing your chance of developing lung cancer. So, understanding your risk factors is a powerful tool in taking charge of your health. Stay informed, make healthy choices, and talk to your healthcare team about personalized strategies to reduce your risk. Remember, knowledge is key!

"Really, anyone with lungs can get lung cancer."

-Catherine Madaffari, M.D., a lung cancer fighter, and a physician in Community Internal Medicine at the Mayo Clinic.

Smoking: The leading risk factor

Man Smoking Cigarette

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Till today, smoking remains the leading risk factor for lung cancer, accounting for 80-90% of all lung cancer cases. While smoking can potentially increase the risk of developing any subtype of lung cancer, it is particularly strongly linked to a specific subtype known as small cell lung cancer (SCLC).

Any form of smoking can increase the risk of lung cancer, such as cigars, pipes, e-cigarettes and even marijuana. These forms of smoking have been investigated for their association with lung cancer.

Smoking takes the lead as the primary risk factor for lung cancer, contributing to 80-90% of cases. The longer and heavier the smoking habit, the higher the risk. The likelihood of developing lung cancer is 20 times higher for smokers compared to non-smokers. This risk is not limited to cigarettes – cigars, pipes, and e-cigarettes can increase the likelihood of lung cancer.

Related: Puff Or Pass? Exploring The Link Between Marijuana And Lung Cancer

Secondhand smoke: A silent threat

Woman Inhaling Secondhand Smoke

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Regular exposure to secondhand smoke, especially in childhood, can elevate your chances of developing lung cancer. Nearly 70% of youth in smoking households are exposed to harmful secondhand smoke. More than 7,000 chemical compounds are found in secondhand smoke, with 69 of them known to cause cancers, including lung cancer.

Aging: A natural culprit

Portrait of a Woman Ageing

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As we age, cancer-causing mutations accumulate naturally. This process, a result of normal aging, is inevitable and may contribute to the development of lung cancer over time.

Gender disparities: Unveiling unique risks

Lung cancer in never-smokers occurs more frequently in females, often at an earlier age. Genetic predispositions, like the EGFR mutation, common among Asian females, play a role, making it crucial to recognize and address women's distinctive risks.

Radon gas exposure

Radon Element in Periodic Table

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Radon is the second leading risk factor of cancer, especially among never-smokers. Epidemiological studies have confirmed a link between radon exposure and an elevated risk of lung cancer. Prolonged exposure to high radon levels increases the likelihood of developing lung cancer. Radon gas breaks down into solid radioactive elements, known as radon progenies, which can adhere to surfaces. When inhaled, these radioactive elements attach to lung linings and emit radiation, leading to DNA mutations in lung cells, ultimately causing cancer.

Related: Radon-Induced Lung Cancer: the Silent Threat to Non-Smokers

Asbestos exposure

Construction Workers Wearing PPE Tiling Roof Asbestos

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Asbestos minerals naturally exist in the environment. Its widespread use in commercial and industrial applications is attributed to its resistance to fire, chemicals, and electricity.

Asbestos exposure stands as the leading occupational risk factor for lung cancer. Individuals at risk often work in mines and places where asbestos insulation is utilized.

Those exposed to asbestos are five times more likely to develop lung cancer. Due to government regulations, the incorporation of asbestos in commercial and industrial products has significantly reduced in recent times.

Asbestos exposure is also associated with a higher risk of malignant pleural mesothelioma, a rare cancer that originates from the lining of the lungs (but is not characterized as lung cancer).

Arsenic in drinking water and food

Arsenic on Periodic Table

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Arsenic, a known carcinogen, naturally occurs in the environment and some man-made products. In Bangladesh, as well as in some countries in South America and East Asia, drinking water sources contain high levels of arsenic, resulting in significantly higher rates of lung cancer in these areas.

The U.S. regulates the arsenic level in drinking water, testing it through The Environmental Protection Agency (EPA) and the Food and Drug Administration (FDA). For most Americans, food represents the largest source of arsenic exposure. Rice, a staple food for many population groups and a major ingredient in many food products for infants and young children, can absorb inorganic arsenic from the soil and water.

Air pollution

City Air Pollution

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The World Health Organization (WHO) identifies air pollution as a risk factor for lung cancer. Sources of air pollution include wildfire and smog from urban traffic emissions, coal burning and other industrial activities. The WHO recommends individuals not be exposed to an annual average concentration of particulate matter with 2.5µm diameters (PM2.5) greater than 5 micrograms per cubic meter. However, in the U.S., over eight million people reside in areas exceeding this limit.

Related: Air Pollution as Lung Cancer Risk

Previous lung diseases or injuries

Pre-existing lung diseases or injuries can create an environment in the lungs conducive to the development of lung cancer. Chronic lung inflammation, such as chronic obstructive pulmonary disease (COPD) and other lung infections, can damage lung tissue and increase the likelihood of mutations. Some individuals may have genetic predispositions making them more susceptible to both lung diseases and lung cancer. It is essential for individuals with a history of lung diseases or injuries to be vigilant about their lung health and take steps to reduce risk factors, such as smoking and exposure to environmental toxins.

Family history and genetics

Cancer, a genetic disease characterized by abnormal functioning and uncontrolled growth of cells due to gene alteration, may have a hereditary component. Over a lifetime, people acquire and accumulate genetic mutations from exposure to various environmental elements, leading to cancer development.

Related: Genetics Of Lung Cancer and How To Test Them

Other carcinogens

Industrialization has led to the widespread use of various chemicals and technologies that can release carcinogenic substances into the environment or expose workers to them. Some of these carcinogens are by-products of industrial processes, while others are used in industrial applications:

  • Uranium ores are used in mines and processing plants, as well as activities in nuclear facilities. These industrial processes can release radioactive materials.
  • Arsenic, beryllium, cadmium, and nickel compounds are used in industrial settings for various purposes, including manufacturing and metalworking.
  • Diesel engines, commonly used in transportation and heavy machinery, emit exhaust fumes containing harmful substances.

It is important to take note of any potential risks that may affect your health. If you believe that you are exposed to any of the risks listed above, it is highly recommended to visit a medical professional. By doing so, you can undergo tests that can lead to an early detection of any health issues. This can help in getting better treatment options with more favorable outcomes. Being well-informed and proactive can go a long way in ensuring your overall health and well-being.

Related: New updates of lung cancer risk factors that you need to know

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This article has been medically reviewed and fact-checked to ensure our content is informed by the latest research in cancer, global and nationwide guidelines and clinical practice.

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